Tissue-Specific Microparticles Improve Organoid Microenvironment for Efficient Maturation of Pluripotent Stem-Cell-Derived Hepatocytes

Liver organoids (LOs) are receiving considerable attention for their potential use in drug screening, disease modeling, and transplantable constructs. Hepatocytes, as the key component of LOs, are isolated from the liver or differentiated from pluripotent stem cells (PSCs). PSC-derived hepatocytes a...

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Veröffentlicht in:Cells
Hauptverfasser: Zahmatkesh, Ensieh, Ghanian, Mohammad Hossein, Zarkesh, Ibrahim, Farzaneh, Zahra, Halvaei, Majid, Heydari, Zahra, Moeinvaziri, Farideh, Othman, Amnah, Ruoß, Marc, Piryaei, Abbas, Gramignoli, Roberto, Yakhkeshi, Saeed, Nüssler, Andreas, Najimi, Mustapha, Baharvand, Hossein, Vosough, Massoud
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2021
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8224093/
https://ncbi.nlm.nih.gov/pubmed/34063948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10061274
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