Human Nasal and Lung Tissues Infected Ex Vivo with SARS-CoV-2 Provide Insights into Differential Tissue-Specific and Virus-Specific Innate Immune Responses in the Upper and Lower Respiratory Tract

The nasal mucosa constitutes the primary entry site for respiratory viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). While the imbalanced innate immune response of end-stage coronavirus disease 2019 (COVID-19) has been extensively studied, the earliest stages of SARS-...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Alfi, Or, Yakirevitch, Arkadi, Wald, Ori, Wandel, Ori, Izhar, Uzi, Oiknine-Djian, Esther, Nevo, Yuval, Elgavish, Sharona, Dagan, Elad, Madgar, Ory, Feinmesser, Gilad, Pikarsky, Eli, Bronstein, Michal, Vorontsov, Olesya, Jonas, Wayne, Ives, John, Walter, Joan, Zakay-Rones, Zichria, Oberbaum, Menachem, Panet, Amos, Wolf, Dana G.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2021
Sujets:
Virus-Cell Interactions
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223920/
https://ncbi.nlm.nih.gov/pubmed/33893170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00130-21
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