Alternative Complement Pathway Is Activated and Associated with Galactose-Deficient IgA(1) Antibody in IgA Nephropathy Patients

BACKGROUND: Galactose-deficient IgA(1) (Gd-IgA(1)) and alternative complement pathway activation are considered to be involved in the pathogenesis of IgA nephropathy (IgAN). Nevertheless, the relationships between alternative pathway activation and disease activity or Gd-IgA(1) level remains unclear...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Chiu, Yen-Ling, Lin, Wei-Chou, Shu, Kai-Hsiang, Fang, Yi-Wen, Chang, Fan-Chi, Chou, Yu-Hsiang, Wu, Ching-Fang, Chiang, Wen-Chih, Lin, Shuei-Liong, Chen, Yung-Ming, Wu, Ming-Shiou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223746/
https://ncbi.nlm.nih.gov/pubmed/34177889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.638309
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