LLGL2 Increases Ca(2+) Influx and Exerts Oncogenic Activities via PI3K/AKT Signaling Pathway in Hepatocellular Carcinoma

BACKGROUND: Lethal giant larvae (Lgl), scaffolding proteins, regulate the epithelial cell apicobasal polarity in Drosophila. They play important roles in asymmetric cell division, cell migration, and progenitor cells self-renewal as tumor suppressors. One of Lgl mammalian homologues proteins, LLGL2...

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Dades bibliogràfiques
Publicat a:Front Oncol
Autors principals: Leng, Shusheng, Xie, Fei, Liu, Junyi, Shen, Junyi, Quan, Guangqian, Wen, Tianfu
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Oncology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223678/
https://ncbi.nlm.nih.gov/pubmed/34178676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.683629
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