In vitro zinc supplementation alters synaptic deficits caused by autism spectrum disorder-associated Shank2 point mutations in hippocampal neurons

Autism Spectrum Disorders (ASDs) are neurodevelopmental disorders characterised by deficits in social interactions and repetitive behaviours. ASDs have a strong genetic basis with mutations involved in the development and function of neural circuitry. Shank proteins act as master regulators of excit...

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Vydáno v:Mol Brain
Hlavní autoři: Vyas, Yukti, Jung, Yewon, Lee, Kevin, Garner, Craig C., Montgomery, Johanna M.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Micro Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8223320/
https://ncbi.nlm.nih.gov/pubmed/34167580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-021-00809-3
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