Caspases and therapeutic potential of caspase inhibitors in moderate–severe SARS‐CoV‐2 infection and long COVID

BACKGROUND: COVID‐19 can present with lymphopenia and extraordinary complex multiorgan pathologies that can trigger long‐term sequela. AIMS: Given that inflammasome products, like caspase‐1, play a role in the pathophysiology of a number of co‐morbid conditions, we investigated caspases across the s...

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Publicado en:Allergy
Main Authors: Plassmeyer, Matthew, Alpan, Oral, Corley, Michael J., Premeaux, Thomas A., Lillard, Kimberleigh, Coatney, Paige, Vaziri, Tina, Michalsky, Suzan, Pang, Alina P. S., Bukhari, Zaheer, Yeung, Stephen T., Evering, Teresa H., Naughton, Gail, Latterich, Martin, Mudd, Philip, Spada, Alfred, Rindone, Nicole, Loizou, Denise, Ulrik Sønder, Søren, Ndhlovu, Lishomwa C., Gupta, Raavi
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2021
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ORIGINAL ARTICLES
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222863/
https://ncbi.nlm.nih.gov/pubmed/33993490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14907
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