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Caspases and therapeutic potential of caspase inhibitors in moderate–severe SARS‐CoV‐2 infection and long COVID

BACKGROUND: COVID‐19 can present with lymphopenia and extraordinary complex multiorgan pathologies that can trigger long‐term sequela. AIMS: Given that inflammasome products, like caspase‐1, play a role in the pathophysiology of a number of co‐morbid conditions, we investigated caspases across the s...

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Detalhes bibliográficos
Publicado no:Allergy
Main Authors: Plassmeyer, Matthew, Alpan, Oral, Corley, Michael J., Premeaux, Thomas A., Lillard, Kimberleigh, Coatney, Paige, Vaziri, Tina, Michalsky, Suzan, Pang, Alina P. S., Bukhari, Zaheer, Yeung, Stephen T., Evering, Teresa H., Naughton, Gail, Latterich, Martin, Mudd, Philip, Spada, Alfred, Rindone, Nicole, Loizou, Denise, Ulrik Sønder, Søren, Ndhlovu, Lishomwa C., Gupta, Raavi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222863/
https://ncbi.nlm.nih.gov/pubmed/33993490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/all.14907
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