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Tripterygium glycoside suppresses epithelial-to-mesenchymal transition of diabetic kidney disease podocytes by targeting autophagy through the mTOR/Twist1 pathway

Tripterygium glycoside (TG) is a traditional Chinese medicine extract with immunosuppressive, anti-inflammatory and anti-renal fibrosis effects. Epithelial-mesenchymal transition (EMT) and cell apoptosis are considered to be the major cause of podocyte injury in diabetic kidney disease (DKD). Howeve...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: Tao, Mei, Zheng, Danna, Liang, Xudong, Wu, Diandian, Hu, Kang, Jin, Juan, He, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222798/
https://ncbi.nlm.nih.gov/pubmed/34165172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2021.12231
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