BPC 157 as a Therapy for Retinal Ischemia Induced by Retrobulbar Application of L-NAME in Rats

Providing NO-system importance, we suggest that one single application of the NOS-blocker L-NAME may induce retinal ischemia in rats, and that the stable pentadecapeptide BPC 157 may be the therapy, since it may interact with the NO-system and may counteract various adverse effects of L-NAME applica...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zlatar, Mirna, Kokot, Antonio, Vuletic, Lovorka Batelja, Masnec, Sanja, Kralj, Tamara, Perisa, Marija Milkovic, Barisic, Ivan, Radic, Bozo, Milanovic, Kristina, Drmic, Domagoj, Seiwerth, Sven, Sikiric, Predrag
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222724/
https://ncbi.nlm.nih.gov/pubmed/34177567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.632295
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