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PHGDH Is Upregulated at Translational Level and Implicated in Platin-Resistant in Ovarian Cancer Cells

BACKGROUND: Platinum-based chemotherapy is the first line option for ovarian cancer. The development of resistance to such chemotherapy results in treatment failure, while the underlying mechanisms are poorly understood. METHODS: Clinical samples were collected from Shengjing Hospital of China Medic...

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Pubblicato in:Front Oncol
Autori principali: Bi, Fangfang, An, Yuanyuan, Sun, Tianshui, You, Yue, Yang, Qing
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222667/
https://ncbi.nlm.nih.gov/pubmed/34178629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.643129
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