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Bilayered, Peptide-Biofunctionalized Hydrogels for In Vivo Osteochondral Tissue Repair

Osteochondral defects present a unique clinical challenge due to their combination of phenotypically distinct cartilage and bone, which require specific, stratified biochemical cues for tissue regeneration. Furthermore, the articular cartilage exhibits significantly worse regeneration than bone due...

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Detalles Bibliográficos
Publicado en:Acta Biomater
Main Authors: Guo, Jason L., Kim, Yu Seon, Koons, Gerry L., Lam, Johnny, Navara, Adam M., Barrios, Sergio, Xie, Virginia Y., Watson, Emma, Smith, Brandon T., Pearce, Hannah A., Orchard, Elysse A., van den Beucken, Jeroen J.J.P., Jansen, John A., Wong, Mark E., Mikos, Antonios G.
Formato: Artigo
Idioma:Inglês
Publicado: 2021
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8222183/
https://ncbi.nlm.nih.gov/pubmed/33930575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2021.04.038
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