Age-related defects in autophagy alter the secretion of paracrine factors from bone marrow mononuclear cells

Bone marrow mononuclear cell therapy improves cardiac repair after myocardial infarction (MI), in-part through signaling to resident cardiac cells, such as fibroblasts, which regulate scar formation. The efficacy of cell therapy declines with age, as aging of both donor and recipient cells decreases...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Yeganeh, Azadeh, Alibhai, Faisal J., Tobin, Stephanie W., Lim, Fievel, Wu, Jun, Li, Shuhong, Weisel, Richard D., Li, Ren-Ke
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2021
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221303/
https://ncbi.nlm.nih.gov/pubmed/34088884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.203127
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