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Recent advances in the development of AHR antagonists in immuno-oncology
The arylhydrocarbon receptor (AHR) is a ligand activated transcription factor that controls the expression of a number of immunosuppressive signaling molecules, including the immune checkpoint proteins PD-1/L1 and cytokine IL-10. AHR activation also stimulates the formation and recruitment of tolero...
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| Publicado no: | RSC Med Chem |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
RSC
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221258/ https://ncbi.nlm.nih.gov/pubmed/34223158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1md00015b |
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