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Submonomer synthesis of peptoids containing trans-inducing N-imino- and N-alkylamino-glycines

The use of hydrazones as a new type of submonomer in peptoid synthesis is described, giving access to peptoid monomers that are structure-inducing. A wide range of hydrazones were found to readily react with α-bromoamides in routine solid phase peptoid submonomer synthesis. Conditions to promote a o...

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Publié dans:Chem Sci
Auteurs principaux: Davern, Carolynn M., Lowe, Brandon D., Rosfi, Adam, Ison, Elon A., Proulx, Caroline
Format: Artigo
Langue:Inglês
Publié: The Royal Society of Chemistry 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8221195/
https://ncbi.nlm.nih.gov/pubmed/34221321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d1sc00717c
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