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Articular cartilage- and synoviocyte-binding poly(ethylene glycol) nano-composite microgels as intra-articular drug delivery vehicles for the treatment of osteoarthritis
Intra-articular (IA) injection is an attractive route of administration for the treatment of osteoarthritis (OA). However, free drugs injected into the joint space are rapidly cleared and many of them can induce adverse off-target effects on different IA tissues. To overcome these limitations, we de...
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| Publicat a: | ACS Biomater Sci Eng |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8221079/ https://ncbi.nlm.nih.gov/pubmed/33455260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsbiomaterials.0c00960 |
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