Comparative assessment of in vitro BBB tight junction integrity following exposure to cigarette smoke and e-cigarette vapor: a quantitative evaluation of the protective effects of metformin using small-molecular-weight paracellular markers

BACKGROUND: The blood–brain barrier (BBB) plays a critical role in protecting the central nervous system (CNS) from blood-borne agents and potentially harmful xenobiotics. Our group’s previous data has shown that tobacco smoke (TS) and electronic cigarettes (EC) affect the BBB integrity, increase st...

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Bibliografiske detaljer
Udgivet i:Fluids Barriers CNS
Main Authors: Kadry, Hossam, Noorani, Behnam, Bickel, Ulrich, Abbruscato, Thomas J., Cucullo, Luca
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220771/
https://ncbi.nlm.nih.gov/pubmed/34158083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12987-021-00261-4
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