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Universal capability of 3-ketosteroid Δ(1)-dehydrogenases to catalyze Δ(1)-dehydrogenation of C17-substituted steroids
BACKGROUND: 3-Ketosteroid Δ(1)-dehydrogenases (KSTDs) are the enzymes involved in microbial cholesterol degradation and modification of steroids. They catalyze dehydrogenation between C1 and C2 atoms in ring A of the polycyclic structure of 3-ketosteroids. KSTDs substrate spectrum is broad, even tho...
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| Udgivet i: | Microb Cell Fact |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8220720/ https://ncbi.nlm.nih.gov/pubmed/34162386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-021-01611-5 |
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