Simvastatin-romidepsin combination kills bladder cancer cells synergistically

The HMG-CoA reductase inhibitor simvastatin activates AMP-activated protein kinase (AMPK) and thereby induces histone acetylation. We postulated that combining simvastatin with the histone deacetylase (HDAC) inhibitor romidepsin would kill bladder cancer cells by inducing histone acetylation coopera...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Transl Oncol
Autors principals: Okubo, Kazuki, Miyai, Kosuke, Kato, Kimi, Asano, Takako, Sato, Akinori
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2021
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220249/
https://ncbi.nlm.nih.gov/pubmed/34144348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2021.101154
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars