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Dominant Optic Atrophy (DOA): Modeling the Kaleidoscopic Roles of OPA1 in Mitochondrial Homeostasis

In the year 2000, the discovery of OPA1 mutations as causative for dominant optic atrophy (DOA) was pivotal to rapidly expand the field of mitochondrial dynamics and describe the complex machinery governing this pathway, with a multitude of other genes and encoded proteins involved in neurodegenerat...

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Bibliografske podrobnosti
izdano v:Front Neurol
Main Authors: Del Dotto, Valentina, Carelli, Valerio
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220150/
https://ncbi.nlm.nih.gov/pubmed/34177786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.681326
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