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Dominant Optic Atrophy (DOA): Modeling the Kaleidoscopic Roles of OPA1 in Mitochondrial Homeostasis

In the year 2000, the discovery of OPA1 mutations as causative for dominant optic atrophy (DOA) was pivotal to rapidly expand the field of mitochondrial dynamics and describe the complex machinery governing this pathway, with a multitude of other genes and encoded proteins involved in neurodegenerat...

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Bibliografische gegevens
Gepubliceerd in:Front Neurol
Hoofdauteurs: Del Dotto, Valentina, Carelli, Valerio
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8220150/
https://ncbi.nlm.nih.gov/pubmed/34177786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2021.681326
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