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Heterotypic Tumor Spheroids in Agitation-Based Cultures: A Scaffold-Free Cell Model That Sustains Long-Term Survival of Endothelial Cells

Endothelial cells (ECs) are an important component of the tumor microenvironment, playing key roles in tumor development and progression that span from angiogenesis to immune regulation and drug resistance. Heterotypic tumor spheroids are one of the most widely used in vitro tumor microenvironment m...

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Библиографические подробности
Опубликовано в: :Front Bioeng Biotechnol
Главные авторы: Franchi-Mendes, Teresa, Lopes, Nuno, Brito, Catarina
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2021
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219978/
https://ncbi.nlm.nih.gov/pubmed/34178955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2021.649949
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