Obesity Challenge Drives Distinct Maternal Immune Response Changes in Normal Pregnant and Abortion-Prone Mouse Models

Obesity is prevalent among women of reproductive age and is associated with increased risk of developing multiple pregnancy disorders. Pregnancy must induce immune tolerance to avoid fetal rejection, while obesity can cause chronic inflammation through activating the immune system. Impaired maternal...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Li, Yanhong, Chen, Jiajia, Lin, Yikong, Xu, Ling, Sang, Yifei, Li, Dajin, Du, Meirong
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2021
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219966/
https://ncbi.nlm.nih.gov/pubmed/34177956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.694077
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