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KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer’s disease
Klotho-VS heterozygosity (KL-VS(het)) is associated with reduced risk of Alzheimer’s disease (AD). However, whether KL-VS(het) is associated with lower levels of pathologic tau, i.e., the key AD pathology driving neurodegeneration and cognitive decline, is unknown. Here, we assessed the interaction...
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| Vydáno v: | Nat Commun |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Nature Publishing Group UK
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8219708/ https://ncbi.nlm.nih.gov/pubmed/34158479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-23755-z |
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