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Medial septal GABAergic neurons reduce seizure duration upon optogenetic closed-loop stimulation

Seizures can emerge from multiple or large foci in temporal lobe epilepsy, complicating focally targeted strategies such as surgical resection or the modulation of the activity of specific hippocampal neuronal populations through genetic or optogenetic techniques. Here, we evaluate a strategy in whi...

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Detalhes bibliográficos
Publicado no:Brain
Main Authors: Hristova, Katerina, Martinez-Gonzalez, Cristina, Watson, Thomas C, Codadu, Neela K, Hashemi, Kevan, Kind, Peter C, Nolan, Matthew F, Gonzalez-Sulser, Alfredo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219369/
https://ncbi.nlm.nih.gov/pubmed/33769452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awab042
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