Immunological and Pathological Landscape of Dengue Serotypes 1-4 Infections in Immune-Competent Mice

Dengue virus (DENV), a Flavivirus, causes a broad spectrum of disease in humans with key clinical signs including thrombocytopenia, vascular leakage and hemorrhaging. A major obstacle to understanding DENV immunity has been the lack of a validated immune-competent mouse model. Here, we report the in...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Rathore, Abhay P. S., Mantri, Chinmay K., Tan, Meredith W., Shirazi, Roksana, Nishida, Andrew, Aman, Siti A. B., Morrison, Juliet, St. John, Ashley L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8219075/
https://ncbi.nlm.nih.gov/pubmed/34168651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.681950
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