Compound FC-10696 Inhibits Egress of Marburg Virus

Marburg virus (MARV) VP40 protein (mVP40) directs egress and spread of MARV, in part, by recruiting specific host WW domain-containing proteins via its conserved PPxY late (L) domain motif to facilitate efficient virus-cell separation. We reported previously that small-molecule compounds targeting t...

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Han, Ziying, Ye, Hong, Liang, Jingjing, Shepley-McTaggart, Ariel, Wrobel, Jay E., Reitz, Allen B., Whigham, Alison, Kavelish, Katrina N., Saporito, Michael S., Freedman, Bruce D., Shtanko, Olena, Harty, Ronald N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2021
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218653/
https://ncbi.nlm.nih.gov/pubmed/33846137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00086-21
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