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Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel–Crafts Alkylase

[Image: see text] The construction and engineering of artificial enzymes consisting of abiological catalytic moieties incorporated into protein scaffolds is a promising strategy to realize non-natural mechanisms in biocatalysis. Here, we show that incorporation of the noncanonical amino acid para-am...

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Detalhes bibliográficos
Publicado no:ACS Catal
Main Authors: Leveson-Gower, Reuben B., Zhou, Zhi, Drienovská, Ivana, Roelfes, Gerard
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2021
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218303/
https://ncbi.nlm.nih.gov/pubmed/34168902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscatal.1c00996
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