Extracellular matrix protein tenascin C increases phagocytosis mediated by CD47 loss of function in glioblastoma

Glioblastomas (GBM) are highly infiltrated by myeloid-derived innate immune cells that contribute to the immunosuppressive nature of the brain tumor microenvironment (TME). CD47 has been shown to mediate immune evasion, as the CD47-SIRPα axis prevents phagocytosis of tumor cells by macrophages and o...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Ma, Ding, Liu, Senquan, Lal, Bachchu, Wei, Shuang, Wang, Shuyan, Zhan, Daqian, Zhang, Hao, Lee, Richard S., Gao, Peisong, Lopez-Bertoni, Hernando, Ying, Mingyao, Li, Jian Jian, Laterra, John, Wilson, Mary Ann, Xia, Shuli
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218246/
https://ncbi.nlm.nih.gov/pubmed/30898840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-3125
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