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Two retroviruses packaged in one cell line can combined inhibit the replication of HIV-1 in TZM-bl cells

The cellular protein tetherin tethers the HIV-1 viral particles on the cellular membrane to inhibit the replication of HIV-1. However, the HIV-1 accessory protein Vpu counteracts the antiviral function of tetherin. In this study, two retroviral vector plasmids were constructed. One inhibited the vpu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Virol Sin
Hauptverfasser: Liang, Zhipin, Guo, Zhiyuan, Wang, Xin, Kong, Xiaohong, Liu, Chang
Format: Artigo
Sprache:Inglês
Veröffentlicht: SP Wuhan Institute of Virology, CAS 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8218129/
https://ncbi.nlm.nih.gov/pubmed/23188559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-012-3263-8
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