An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency

Dengue virus (DENV), from the genus flavivirus of the family flaviviridae, causes serious health problems globally. Human monoclonal antibodies (HuMAb) can be used to elucidate the mechanisms of neutralization and antibody-dependent enhancement (ADE) of DENV infections, leading to the development of...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Kotaki, Tomohiro, Kurosu, Takeshi, Grinyo-Escuer, Ariadna, Davidson, Edgar, Churrotin, Siti, Okabayashi, Tamaki, Puiprom, Orapim, Mulyatno, Kris Cahyo, Sucipto, Teguh Hari, Doranz, Benjamin J., Ono, Ken-ichiro, Soegijanto, Soegeng, Kameoka, Masanori
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8217507/
https://ncbi.nlm.nih.gov/pubmed/34155267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92403-9
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi