Mangiferin Alleviates Mitochondrial ROS in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration via Suppression of NF-κB Signaling Pathway

Intervertebral disc degeneration (IVDD), one of the most common clinical diseases worldwide, causes disc herniation and sciatica. Recent studies have identified the involvement of mitochondrial dysfunction, inflammatory responses, and extracellular matrix degradation in IVDD. Mangiferin is known to...

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Spremljeno u:
Bibliografski detalji
Izdano u:Oxid Med Cell Longev
Glavni autori: Yu, Haichao, Hou, Guowei, Cao, Jiankang, Yin, Yanyu, Zhao, Yunpeng, Cheng, Lei
Format: Artigo
Jezik:Inglês
Izdano: Hindawi 2021
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216826/
https://ncbi.nlm.nih.gov/pubmed/34234886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2021/6632786
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