Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants

Etoposide (VP16) is the traditional antitumor agent which has been widely used in a variety of cancers. However, intravenous administration of VP16 was limited in clinical application because of its low aqueous solubility, poor bioavailability and dose-limiting adverse effects. Local chemotherapy wi...

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Bibliographic Details
Published in:Drug Deliv
Main Authors: Wu, Chunsheng, Yi, Xiangting, Xu, Renzhi, Zhang, Maokuan, Xu, Yan, Ma, Yan, Gao, Li, Zha, Zhengbao
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2020
Subjects:
RESEARCH Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216434/
https://ncbi.nlm.nih.gov/pubmed/32611260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10717544.2020.1787558
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