Behavioural impairments after exposure of neonatal mice to propofol are accompanied by reductions in neuronal activity in cortical circuitry

BACKGROUND: Both animal and retrospective human studies have linked extended and repeated general anaesthesia during early development with cognitive and behavioural deficits later in life. However, the neuronal circuit mechanisms underlying this anaesthesia-induced behavioural impairment are poorly...

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Bibliographische Detailangaben
Veröffentlicht in:Br J Anaesth
Hauptverfasser: Zhou, Hang, Xie, Zhongcong, Brambrink, Ansgar M., Yang, Guang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2021
Schlagworte:
Neuroscience and Neuroanaesthesia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216302/
https://ncbi.nlm.nih.gov/pubmed/33641936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bja.2021.01.017
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