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Genome editing in mammalian cells using the CRISPR type I-D nuclease

Adoption of CRISPR–Cas systems, such as CRISPR–Cas9 and CRISPR–Cas12a, has revolutionized genome engineering in recent years; however, application of genome editing with CRISPR type I—the most abundant CRISPR system in bacteria—remains less developed. Type I systems, such as type I-E, and I-F, compr...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Osakabe, Keishi, Wada, Naoki, Murakami, Emi, Miyashita, Naoyuki, Osakabe, Yuriko
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8216271/
https://ncbi.nlm.nih.gov/pubmed/34076237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkab348
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