Targeting WD repeat domain 5 enhances chemosensitivity and inhibits proliferation and programmed death-ligand 1 expression in bladder cancer

BACKGROUND: Chemotherapy and/or immunotherapy are first-line treatments for advanced muscle-invasive bladder cancer (BCa), but the unsatisfactory objective response rate to these treatments yields poor 5-year patient survival. Discovery of therapeutic targets essential for BCa maintenance is critica...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhang, Jingtong, Zhou, Qianghua, Xie, Keji, Cheng, Liang, Peng, Shengmeng, Xie, Ruihui, Liu, Lixuan, Zhang, Yangjie, Dong, Wen, Han, Jinli, Huang, Ming, Chen, Yuelong, Lin, Tianxin, Huang, Jian, Chen, Xu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215817/
https://ncbi.nlm.nih.gov/pubmed/34154613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01989-5
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