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Fractalkine (CX3CL1) and Its Receptor CX3CR1: A Promising Therapeutic Target in Chronic Kidney Disease?

Innate immune cells are key contributors to kidney inflammation and fibrosis. Infiltration of the renal parenchyma by innate immune cells is governed by multiple signalling pathways. Since the discovery of the chemokine fractalkine (CX3CL1) and its receptor, CX3CR1 over twenty years ago, a wealth of...

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Pubblicato in:Front Immunol
Autori principali: Cormican, Sarah, Griffin, Matthew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215706/
https://ncbi.nlm.nih.gov/pubmed/34163473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.664202
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