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Imbalanced Subthreshold Currents Following Sepsis and Chemotherapy: A Shared Mechanism Offering a New Therapeutic Target?

Both sepsis and treatment of cancer with chemotherapy are known to cause neurologic dysfunction. The primary defects seen in both groups of patients are neuropathy and encephalopathy; the underlying mechanisms are poorly understood. Analysis of preclinical models of these disparate conditions reveal...

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Pubblicato in:Neuroscientist
Autori principali: Rich, Mark M., Housley, Stephen N., Nardelli, Paul, Powers, Randall K., Cope, Timothy C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2022
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8215085/
https://ncbi.nlm.nih.gov/pubmed/33345706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1073858420981866
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