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Rab11 is required for lysosome exocytosis through the interaction with Rab3a, Sec15 and GRAB

Lysosomes are dynamic organelles, capable of undergoing exocytosis. This process is crucial for several cellular functions, namely plasma membrane repair. Nevertheless, the molecular machinery involved in this process is poorly understood. Here, we identify Rab11a and Rab11b as regulators of Ca(2+)-...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Escrevente, Cristina, Bento-Lopes, Liliana, Ramalho, José S., Barral, Duarte C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214760/
https://ncbi.nlm.nih.gov/pubmed/34100549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.246694
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