Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis

Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease characterized by myelin damage followed by axonal and ultimately neuronal loss. The etiology and physiopathology of MS are still elusive, and no fully effective therapy is yet available. We investigated the role in MS of au...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Patergnani, Simone, Bonora, Massimo, Ingusci, Selene, Previati, Maurizio, Marchi, Saverio, Zucchini, Silvia, Perrone, Mariasole, Wieckowski, Mariusz R., Castellazzi, Massimiliano, Pugliatti, Maura, Giorgi, Carlotta, Simonato, Michele, Pinton, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214668/
https://ncbi.nlm.nih.gov/pubmed/34099564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020078118
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