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PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment

Colorectal cancer (CRC) stem cells are resistant to cancer therapy and are therefore responsible for tumour progression after conventional therapy fails. However, the molecular mechanisms underlying the maintenance of stemness are poorly understood. In this study, we identified PCGF1 as a crucial ep...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Ji, Guangyu, Zhou, Wenjuan, Du, Jingyi, Zhou, Juan, Wu, Dong, Zhao, Man, Yang, Liping, Hao, Aijun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214626/
https://ncbi.nlm.nih.gov/pubmed/34148069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03914-2
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