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PCGF1 promotes epigenetic activation of stemness markers and colorectal cancer stem cell enrichment

Colorectal cancer (CRC) stem cells are resistant to cancer therapy and are therefore responsible for tumour progression after conventional therapy fails. However, the molecular mechanisms underlying the maintenance of stemness are poorly understood. In this study, we identified PCGF1 as a crucial ep...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Ji, Guangyu, Zhou, Wenjuan, Du, Jingyi, Zhou, Juan, Wu, Dong, Zhao, Man, Yang, Liping, Hao, Aijun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214626/
https://ncbi.nlm.nih.gov/pubmed/34148069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03914-2
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