Deletion of SarX Decreases Biofilm Formation of Staphylococcus aureus in a Polysaccharide Intercellular Adhesin (PIA)-Dependent Manner by Downregulating spa

INTRODUCTION: Biofilm formation by Staphylococcus aureus is an important virulence determinant mediated by the polysaccharide intercellular adhesin (PIA) encoded by the ica operon or mediated by surface and extracellular proteins. SarX is a 250-residue two-domain SarA homolog that activates spa tran...

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Detalhes bibliográficos
Publicado no:Infect Drug Resist
Main Authors: Hao, Zhihao, Guo, Yinjuan, Rao, Lulin, Yu, Jingyi, Zhan, Qing, Xu, Yanlei, Wang, Bingjie, Wu, Xiaocui, Yu, Fangyou
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2021
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214526/
https://ncbi.nlm.nih.gov/pubmed/34163189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IDR.S305650
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