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Using adalimumab serum concentration to choose a subsequent biological DMARD in rheumatoid arthritis patients failing adalimumab treatment (ADDORA-switch): study protocol for a fully blinded randomised superiority test-treatment trial

BACKGROUND: A substantial proportion of rheumatoid arthritis (RA) patients discontinues treatment with tumour necrosis factor inhibitors (TNFi) due to inefficacy or intolerance. After the failure of treatment with a TNFi, treatment can be switched to another TNFi or a bDMARD with a different mode of...

詳細記述

保存先:
書誌詳細
出版年:Trials
主要な著者: Wientjes, Maike H. M., Atiqi, Sadaf, Wolbink, Gerrit Jan, Nurmohamed, Michael T., Boers, Maarten, Rispens, Theo, de Vries, Annick, van Vollenhoven, Ronald F., van den Bemt, Bart J. F., den Broeder, Alfons A.
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214249/
https://ncbi.nlm.nih.gov/pubmed/34147123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-021-05358-7
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