Adipose Triglyceride Lipase Loss Promotes a Metabolic Switch in A549 Non–Small Cell Lung Cancer Cell Spheroids

Cancer cells undergo complex metabolic adaptations to survive and thrive in challenging environments. This is particularly prominent for solid tumors, where cells in the core of the tumor are under severe hypoxia and nutrient deprivation. However, such conditions are often not recapitulated in the t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Mol Cell Proteomics
Autori principali: Honeder, Sophie, Tomin, Tamara, Nebel, Laura, Gindlhuber, Jürgen, Fritz-Wallace, Katarina, Schinagl, Maximilian, Heininger, Christoph, Schittmayer, Matthias, Ghaffari-Tabrizi-Wizsy, Nassim, Birner-Gruenberger, Ruth
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2021
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8214150/
https://ncbi.nlm.nih.gov/pubmed/33992777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcpro.2021.100095
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