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Hypoxic postconditioning promotes mitophagy against transient global cerebral ischemia via PINK1/Parkin-induced mitochondrial ubiquitination in adult rats

Mitophagy alleviates neuronal damage after cerebral ischemia by selectively removing dysfunctional mitochondria. Phosphatase and tensin homolog (PTEN) induced putative kinase 1 (PINK1)/Parkin-mediated mitophagy is the most well-known type of mitophagy. However, little is known about the role of PINK...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wen, Haixia, Li, Luxi, Zhan, Lixuan, Zuo, Yunyan, Li, Kongping, Qiu, Meiqian, Li, Heying, Sun, Weiwen, Xu, En
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213752/
https://ncbi.nlm.nih.gov/pubmed/34145219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-021-03900-8
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