Basement membrane collagen IV deficiency promotes abdominal aortic aneurysm formation

Abdominal aortic aneurysm (AAA) is a complex disease which is incompletely accounted for. Basement membrane (BM) Collagen IV (COL4A1/A2) is abundant in the artery wall, and several lines of evidence indicate a protective role of baseline COL4A1/A2 in AAA development. Using Col4a1/a2 hemizygous knock...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Steffensen, L. B., Stubbe, J., Lindholt, J. S., Beck, H. C., Overgaard, M., Bloksgaard, M., Genovese, F., Holm Nielsen, S., Tha, M. L. T., Bang-Moeller, S. K., Hong Lin, M. K. T., Larsen, J. H., Hansen, D. R., Jones, G. T., Bown, M. J., Karsdal, M. A., Rasmussen, L. M.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213747/
https://ncbi.nlm.nih.gov/pubmed/34145342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-92303-y
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