The pan-cancer lncRNA PLANE regulates an alternative splicing program to promote cancer pathogenesis

Genomic amplification of the distal portion of chromosome 3q, which encodes a number of oncogenic proteins, is one of the most frequent chromosomal abnormalities in malignancy. Here we functionally characterise a non-protein product of the 3q region, the long noncoding RNA (lncRNA) PLANE, which is u...

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Pubblicato in:Nat Commun
Autori principali: Teng, Liu, Feng, Yu Chen, Guo, Su Tang, Wang, Pei Lin, Qi, Teng Fei, Yue, Yi Meng, Wang, Shi Xing, Zhang, Sheng Nan, Tang, Cai Xia, La, Ting, Zhang, Yuan Yuan, Zhao, Xiao Hong, Gao, Jin Nan, Wei, Li Yuan, Zhang, Didi, Wang, Jenny Y., Shi, Yujie, Liu, Xiao Ying, Li, Jin Ming, Cao, Huixia, Liu, Tao, Thorne, Rick F., Jin, Lei, Shao, Feng-Min, Zhang, Xu Dong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213729/
https://ncbi.nlm.nih.gov/pubmed/34145290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24099-4
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