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Activation mechanism of Drosophila cryptochrome through an allosteric switch

Cryptochromes are signaling proteins activated by photoexcitation of the flavin adenine dinucleotide (FAD) cofactor. Although extensive research has been performed, the mechanism for this allosteric process is still unknown. We constructed three computational models, corresponding to different redox...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Wang, Yingjie, Veglia, Gianluigi, Zhong, Dongping, Gao, Jiali
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213227/
https://ncbi.nlm.nih.gov/pubmed/34144991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abg3815
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