Compassionate use of ruxolitinib in patients with SARS‐Cov‐2 infection not on mechanical ventilation: Short‐term effects on inflammation and ventilation

ABSTRACT: Ruxolitinib is an anti‐inflammatory drug that inhibits the Janus kinase‐signal transducer (JAK‐STAT) pathway on the surface of immune cells. The potential targeting of this pathway using JAK inhibitors is a promising approach in patients affected by coronavirus disease 2019 (COVID‐19). Rux...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Transl Sci
Prif Awduron: Mortara, Andrea, Mazzetti, Simone, Margonato, Davide, Delfino, Pietro, Bersano, Chiara, Catagnano, Francesco, Lauriola, Marinella, Grosso, Paolo, Perseghin, Gianluca, Ippoliti, Giovanbattista
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212747/
https://ncbi.nlm.nih.gov/pubmed/33403775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12971
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