A target‐mediated drug disposition population pharmacokinetic model of GC1118, a novel anti‐EGFR antibody, in patients with solid tumors

ABSTRACT: GC1118 is a monoclonal antibody for epidermal growth factor receptor (EGFR) that is currently under clinical development to treat patients with solid tumors. In this study, the pharmacokinetics (PKs) of GC1118 were modeled in solid tumor patients who received a 2‐h intravenous infusion of...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Chung, Tae Kyu, Lee, Hyun A., Park, Sang‐In, Oh, Do‐Youn, Lee, Keun‐Wook, Kim, Jin Won, Kim, Jee Hyun, Woo, Ahmi, Lee, Su Jin, Bang, Yung‐Jue, Lee, Howard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212746/
https://ncbi.nlm.nih.gov/pubmed/33382918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12963
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