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Real‐world evidence of population differences in allopurinol‐related severe cutaneous adverse reactions in East Asians: A population‐based cohort study

ABSTRACT: Allopurinol‐related severe cutaneous adverse reactions (SCARs) are strongly associated with HLA‐B*58:01, the allele frequency (AF) of which is largely different among East Asians. However, evidence of population differences in SCAR development and relevance of genetic and/or other risk fac...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Sato, Tsugumichi, Cheng, Ching‐Lan, Park, Heung‐Woo, Kao Yang, Yea‐Huei, Yang, Min‐Suk, Fujita, Mizuki, Kumagai, Yuji, Tohkin, Masahiro, Saito, Yoshiro, Sai, Kimie
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8212744/
https://ncbi.nlm.nih.gov/pubmed/33382928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12964
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