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DNA-Functionalized Metal–Organic Framework Nanoparticles for Intracellular Delivery of Proteins
Due to their large size, charged surfaces, and environmental sensitivity, proteins do not naturally cross cell-membranes in intact form and, therefore, are difficult to deliver for both diagnostic and therapeutic purposes. Based upon the observation that clustered oligonucleotides can naturally enga...
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| Pubblicato in: | J Am Chem Soc |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8212418/ https://ncbi.nlm.nih.gov/pubmed/30669839 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b12705 |
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