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Machine learning differentiates enzymatic and non-enzymatic metals in proteins

Metalloenzymes are 40% of all enzymes and can perform all seven classes of enzyme reactions. Because of the physicochemical similarities between the active sites of metalloenzymes and inactive metal binding sites, it is challenging to differentiate between them. Yet distinguishing these two classes...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Feehan, Ryan, Franklin, Meghan W., Slusky, Joanna S. G.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8211803/
https://ncbi.nlm.nih.gov/pubmed/34140507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-021-24070-3
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